Raynaud’s Syndrome, also known as Raynaud’s phenomenon or Raynaud’s disease, is a relatively common condition. It is more likely to occur in women than in men and is often seen in young women living in colder climates. In most cases, it does not even require treatment, as symptoms can be alleviated by keeping warm.

What is Raynaud’s Syndrome?

The hand of a person with Raynaud syndrome during an attack.
The hand of a person with Raynaud syndrome during an attack.

Raynaud’s Syndrome is characterized by numbness and coldness in certain areas of the body when exposed to cold or under stress. The most commonly affected areas are the fingers and toes, although in some cases, the nose, ears, nipples, lips, or knees may also be impacted. In this condition, the small arteries that supply blood to fingers and toes constrict in response to cold or stress. This narrowing is usually temporary. Blood flow to the affected area decreases, a condition known as vasospasm.

Types of Raynaud’s Syndrome

Raynaud’s Syndrome can be classified as either primary or secondary. When the condition occurs on its own without any underlying cause, it is called “primary” Raynaud’s disease. The primary form is more common and typically appears between the ages of 15 and 25.

However, when Raynaud’s Syndrome is associated with an underlying disease—often a rheumatic or autoimmune disorder—it is classified as secondary Raynaud’s Syndrome. Diseases that can cause secondary Raynaud’s Syndrome usually include connective tissue diseases or autoimmune disorders, such as:

  • Systemic Lupus Erythematosus (SLE)
  • Scleroderma
  • CREST Syndrome
  • Buerger’s Disease (Thromboangiitis obliterans)
  • Sjögren’s Syndrome
  • Rheumatoid Arthritis
  • Atherosclerosis
  • Polymyositis
  • Blood disorders like Cryoglobulinemia
  • Thyroid diseases
  • Pulmonary Hypertension

What Causes Raynaud’s Syndrome?

The exact cause of Raynaud’s Syndrome is not well understood. It is thought that conditions like thrombocytosis (an increased number of platelets) and polycythemia (an elevated number of red blood cells), which increase blood viscosity, as well as abnormalities in certain receptors that regulate blood vessel constriction and dilation, may contribute to Raynaud’s Syndrome. Some factors that may increase the risk of developing Raynaud’s disease include:

  1. Connective tissue diseases
  2. Autoimmune disorders
  3. Exposure to chemicals
  4. Smoking
  5. Trauma
  6. Repetitive movements such as typing or using vibrating tools like jackhammers
  7. Certain medications
  8. Carpal Tunnel Syndrome

Common Symptoms of Raynaud’s Syndrome

The symptoms of Raynaud’s Syndrome are triggered by cold weather or stress. Once the stressor is removed or the affected area is warmed, the symptoms usually subside. The most common symptoms include:

  • Coldness of the affected area: The affected region becomes cold due to reduced blood flow.
  • Three-phase color change: The affected area first turns white, then blue-purple, and finally red. The area turns white because of reduced blood flow, then blue-purple due to a lack of oxygen (a condition called cyanosis), leading to numbness and coldness. When blood flow returns, the area becomes red. Once the attack is over, there may be a sharp, aching pain in the area. Raynaud’s attacks can last less than a minute or continue for hours.
  • Numbness and tingling: Due to insufficient blood supply to the nerves in the affected area.
  • Swelling: Sometimes, the affected area may swell as blood flow returns after an attack.

Common Misconceptions About Raynaud’s Syndrome

There is a general lack of awareness and understanding about Raynaud’s Syndrome in society, leading to several misconceptions. Some of the most common misconceptions are:

  • Raynaud’s Syndrome is rare: It’s difficult to pinpoint the exact number of people affected by Raynaud’s Syndrome, as only one in ten people with the condition seek medical help. Studies suggest that about 5% of the population has Raynaud’s Syndrome, and this number can rise to 20% in women of reproductive age.

 

  • Raynaud’s Syndrome can be documented with simple medical tests: There is no specific medical test for Raynaud’s Syndrome. Most diagnoses are based on the patient’s medical history. Although it was once common to provoke symptoms by immersing the hands in ice water, this practice has been abandoned due to the rare possibility of irreversible symptoms.

 

  • Raynaud’s Syndrome only affects fingers and toes: While fingers and toes are the most commonly affected areas, it has also been reported to affect the nose, ears, nipples, lips, and even the tongue. During cold or stress, the body redirects blood flow to vital organs like the heart and brain, leading to reduced blood flow to other areas.

 

  • Raynaud’s Syndrome is a type of cold allergy: Raynaud’s Syndrome is not an allergic reaction to cold. In cases of cold allergy, a condition called “cold urticaria” occurs, which involves itching and rashes. It is important to distinguish between cold allergies and Raynaud’s Syndrome.

 

  • Raynaud’s Syndrome only occurs in winter or cold climates: Triggers for Raynaud’s attacks can include exposure to air conditioning, swimming, holding a cold object, or being near a freezer. It’s not only extreme cold that can cause an attack.

How is Raynaud’s Syndrome Treated?

The main goals of Raynaud’s Syndrome treatment are to reduce the frequency and severity of attacks and to prevent tissue damage and loss in the fingers and toes. Patients with the primary form usually do not require medication, while those with the secondary form may need medication. Non-medication strategies for managing Raynaud’s Syndrome include:

  • Be proactive during an attack: Do not ignore Raynaud’s attacks. Appropriate measures can reduce the severity and duration of an attack. The best initial step is to warm the hands and feet. Avoid staying outside in cold weather, and if possible, move indoors. Warm the affected area with lukewarm water, avoiding extreme heat.
  • Keep yourself warm: Protect the whole body from cold exposure, not just the hands and feet. Dress appropriately for the weather, and wear a hat or cap in cold climates since significant heat loss occurs through the scalp.
  • Moisturize: Keep the skin hydrated to prevent dryness and cracks caused by cold.
  • Avoid smoking: Nicotine in cigarettes causes blood vessels to constrict and lowers body temperature, which can trigger an attack. If you smoke, quitting is crucial.
  • Learn to manage stress: Stress is a major trigger for Raynaud’s attacks. Identifying and avoiding stressful situations can help reduce the number of attacks.
  • Exercise regularly: Regular exercise is an important part of managing Raynaud’s Syndrome, as it promotes overall well-being. However, avoid exercising in cold weather.

For patients with secondary Raynaud’s Syndrome, medication may be necessary. The most effective and safest drug class for treating Raynaud’s Syndrome is calcium channel blockers, which help to dilate small arteries. They are also effective in healing ulcers on the fingers and toes caused by Raynaud’s Syndrome.

Foods That Help With Raynaud’s Syndrome

Diet is another important aspect for people living with Raynaud’s Syndrome. A balanced and regular diet should be maintained, avoiding substances like caffeine, nicotine, and alcohol. Evening primrose oil, ginkgo biloba, and fish oils may help improve Raynaud’s Syndrome. Ginger, garlic, and spicy foods can also help reduce attacks.

Proteins, one of the most fundamental food groups, strengthen tissue and repair damaged areas. Increasing dietary protein intake may speed up the healing of ulcers caused by Raynaud’s Syndrome in the fingers and toes. It’s important to consume these foods under the supervision and recommendation of a doctor.

Although most Raynaud’s attacks seem harmless, they have been reported to cause tissue damage and loss. If you experience frequent attacks, if the attacks last a long time, cause infections or wounds, or if your first attack occurred after age 25, be sure to see a doctor and take care of your health.